Fold Puzzle Database

Fuzzle is a database of evolutionary related protein fragments.

See the latest Fuzzle version here

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Protein Evolution

Find remote evolutionary relationships to your protein of interest.

Protein Universe

Visualize the protein universe from a global perspective.

Relationships between folds

Discover fragments in common between two SCOP domains, families, superfamilies, folds, and classes.


Learn more about the database, methods and analysis tools and make the most of Fuzzle.


Find regions in your protein of interest that are found across the protein space.

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